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This effect is strongly amplified by CYP2E1-mediated oxidative stress, which increases transcription factor activity on these promoters

Oxidized Arachidonic and Adrenic Pes Navigate Cells to Ferroptosis

de Souza JA, Vindis C, Negre-Salvayre A, Rye KA, Couturier M, Therond P, Chantepie S, Salvayre R, Chapman MJ, Kontush A

The enzymes proline hydroxylase and lysyl hydroxylase are important in the formation of the protein collagen

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