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doi: 10.1016/j.envpol.2020.114880 35 NiYHuLYangSNiLMaLZhaoYet al

Copper is a required cofactor for lysyl oxidase (connective-tissue crosslinking), for superoxide dismutase (antioxidant defense), and for enzymes that support angiogenesis, so a molecule that delivers copper in a controlled, cell-usable form has a coherent reason to influence tissue remodeling and vascular biology

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The journal of headache and pain , 16 , 516