The 12-month EFS rate was 83.7% (95% CI, 73.8%94.8%) in the neoadjuvant group and 57.2% (95% CI, 45.1%72.7%) in the adjuvant-alone group.[21][Level of evidence B1] The benefit of neoadjuvant therapy was seen across all subgroups of patients, including those with BRAF pathogenic variants
[ Links ] Fride E, Mechoulam R (1993) Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent
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Even more people have nutrient inadequacies---when intake of a nutrient is above the level usually associated with deficiency but below the estimated average requirement for healthy individuals---suggesting a potential for marginal deficiencies
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