Key properties: Stimulates GH release from the pituitary (not the hypothalamus) Does not significantly raise cortisol or prolactin Short half-life (~2 hours) produces a sharp, pulsatile GH release Does not block somatostatin (the hormone that inhibits GH release) Selective for GH minimal effect on other hormones The selectivity is what makes ipamorelin the preferred GHRP for most protocols
2017 Dec 21;3(1):17040
Managing Your Expectations Wellness is a marathon, not a sprint
There may be increased inflammation in the small intestine from increased mast cell activity
[PubMed: 30689447] (70 year old woman developed seizures within 30 minutes after mistakenly taking an industrial form of ALA [4500 mg] with metabolic acidosis, lactic acidosis [14.9 mmoL], decrease in platelets [140,000 decreasing to 73,000/uL], and hemodynamic instability, responding to supportive therapy within several days)
While research on BPC-157, particularly in United States human trials, is ongoing and has shown promising results, it is primarily available for research purposes