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Industry Funding: From the study, the trial was funded by Eli Lilly

Casella, G

Metallothioneins (MTs) are small, cysteine-rich proteins primarily involved in the metabolism of Zn(II) and Cu(I) ions (Krel and Maret 2017, 2021

Because ALOXs are a nonheme iron-containing enzymes, the presence of iron significantly increases their oxidative activity, and the subsequent generation of PLOOH continues to react with Fe 2+ , generating new lipid radicals

As your body adjusts to the medication, they tend to ease up on their own