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The kidney contributes through hypoxia-induced mitochondrial ROS, NOX4 activation, and angiotensin II-stimulated renin angiotensin aldosterone system (RAAS) pathways, which worsen tubular damage and accelerate CKD progression (62, 63)

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[DOI] [PubMed] [Google Scholar] 9.Owens CW, Belcher RV

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A lump, bruise, or tender patch is a reason to avoid that exact spot until you have guidance and the area has recovered

Overdoing fiber can lead to bloating or discomfort, especially if not spaced out properly