That matters for side effects, dose timing, surgery planning, and decisions about stopping or switching treatment
The study population was relatively small and predominantly female, thus potentially limiting our ability to assess effect size across sex
The study indicates that combining semaglutide with trevogrumab (anti-GDF8/anti-myostatin) helped prevent about half of the lean mass loss typically associated with GLP-1 therapy, while increasing fat loss
Psychopharmacology 240 , 12871298 (2023)
7 In patients who meet these criteria, the ADA preferably recommends use of a GLP-1 RA with proven cardiovascular benefit or an SGLT-2 inhibitor with proven cardiovascular benefit provided they have adequate kidney function
Eating smaller portions more frequently often works better than three large meals