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With regard to pregnancy, breastfeeding or any serious condition a healthcare professional can advise

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Oral dihexa is not pharmacologically viable because the peptide is degraded by gastric acid and pancreatic proteases before absorption, resulting in bioavailability below 5%

While toxic levels are typically only achieved through vitamin supplements, if large quantities of fat-soluble vitamins are consumed, either through foods or supplements, vitamin levels can build up in the liver and fatty tissues, leading to symptoms of toxicity