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The disadvantage is that it can cause vomiting

Most importantly, these metrics help redefine success

A BMI of 30 or more, at least in the western population, is obesity

Spacing food out into four to six smaller meals instead of three large ones helps reduce that burden and keeps digestion moving more comfortably

A Simple Checklist If youre on a GLP-1 or thinking about one, and any of the following apply, its worth having a real conversation with both your prescribing doctor and a maxillofacial surgeon: You have sleep apnea, or you probably do and havent been tested You know or suspect youve got a jaw deformity, bad bite, or facial asymmetry You have ongoing TMJ pain, clicking, locking, or limited opening Youve had jaw surgery before and the results werent complete Youve got an elective jaw, cosmetic, or facial procedure on the calendar Your face or your bite has changed noticeably since you started losing weight Good questions to bring with you: Am I at a stable weight, or am I still losing

one of four oral small-molecule programs under the May 2025 Septerna-Novo collaboration (up to $2.2B total deal value with $200M+ upfront)