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For those who choose to take low-dose GLP-1s, a medical expert also advises seeking out continuous, certified care

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In the over 2500 participants, who were assigned to the 5, 10, and 15 mg doses of tirzepatide and placebo, the percent weight changes were both statistically and clinically significant compared with placebo

But: Considering these are prescription drugs, not over-the-counter wellness buys, choosing the right provider mattersand not every service offering GLP-1s actually supports safe, supervised microdosing

Microdosing could also be rising in popularity as a way for these medicines to be more cost-effective during shortages. She says taking a low dose may also be appropriate for people who: want to avoid or minimize side effects of a particular medication, or have a history of being sensitive to medication side effects