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The aggregation and denaturation that follow repeated freeze-thaw cycles will degrade both peptides, and unlike the lyophilized state, the damage is not reversible

It appears to activate Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) and facilitates its internalization within endothelial cells (cells lining blood vessels)

Some clinicians combine both approaches, using PRP to deliver growth factors while simultaneously administering peptides to enhance cellular responsiveness

This might also be seen in further prolonged studies (Figure 4, Figure 5 and Figure 6)

(March 2011)

Any leftover solution should be thrown away after use