Liquid (reconstituted) tirzepatide: Once tirzepatide is in solution, all the degradation pathways discussed earlier become active
it's a sophisticated enhancement of a natural process
In addition, glutamate signal transduction in neurons is augmented by dopamine, therefore, nigral neurons, i.e., substantia nigra pars compacta neurons, are highly susceptible to glutamate excitotoxicity effects (85)
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This damage leads to cupping of the optic nerve and ultimate visual loss