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JAMA Network Open, 6(5), e2314493

This equalizes the pressure and makes it easier to draw the liquid

For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment

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TB-500 is systemically acting - distributes throughout the body via actin regulation, dosed in milligrams (25 mg), given twice weekly