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Oral GLP-1 therapy is quickly reshaping how we treat type 2 diabetes, especially for patients who hesitate at the thought of injections

Changes in CYP7A1 activity can upset the bile acid balance and interfere with liver metabolism (Low et al ., 2020)

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Feb 2005;6(1):15-22

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Four hundred and thirty (88%) of these patients have conditions for which the drug is a proven benefit , so the increased frequency of injections accounts for most of the observed excess