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Methylene blue (MB), chemically known as methylthioninium chloride , is a phenothiazine derivative

The extensive breadth of these different molecules highlights the diversity of astrocyte reactivity not only across disorders, but within the same disorder at different timepoints or in different CNS locations

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In addition, prolonged exposure to pharmacologic doses of long-acting GLP-1 RAs induces tachyphylaxis for the effects on gastric emptying, and that is why nausea vanishes quickly after the beginning of treatment in most patients [19]

[PubMed: 16020735] 862

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