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However, oral semaglutide contains an absorption enhancer that may enter breast milk with unknown effects, so only injectable formulations are considered appropriate during breastfeeding

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Accessed October 3, 2024

This information, interpreted with your provider, can support a more evidence-informed discussion about whether GLP-1 therapy fits your unique clinical picture

329,330 In degenerative joint diseases like OA, the metabolic balance of chondrocytes is disrupted, leading to the overproduction of degrading enzymes and inflammatory mediators, including iNOS, MMP-13, and ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5), which participate in cartilage degradation and inflammatory processes