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Many protocols combine both approaches for maximum effect, typically running 12 to 16 weeks minimum before visible density changes become apparent

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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Reger M., Watson G., Frey W., Baker L., Cholerton B., Keeling M., Belongia D., Fishel M., Plymate S., Schellenberg G., et al

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