The ability of GLP-1RAs to promote weight loss is particularly relevant for MASLD due to the close association between obesity and liver fat accumulation
I think this is what everybody deals with to some degree as they age
An FDA announcement that semaglutide injection products, the GLP-1 medication in the blockbuster drugs Wegovy and Ozempic, are no longer in shortage
Due to the slowing of the gastrointestinal tract caused by GLP-1 receptor agonists, some patients may experience stomach pains or constipation
Challenges of insulin therapy include weight gain, the need for education and titration for optimal efficacy, risk of hypoglycaemia, the need for regular glucose monitoring, and cost
46 Adverse Effects and Tolerability of GLP-1RAs in Clinical Practice Although the cardiovascular benefits of GLP-1RAs are significant, their use is commonly associated with well-characterised adverse effects that can affect tolerability and long-term medication adherence, as detailed below