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They were initially defined as secretory GPX, but later studies have shown that both enzymes are localized to the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins (Figure 8)

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Cagrilintide + rztd Combines amylin signaling with GIP/GLP-1 co-agonism for broader metabolic and satiety effects

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