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Pooled analysis from eight cohort studies estimated that GLP-1 RA therapy increases the relative risk of inadequate cleansing by 80%, yielding a number needed to repeat (NNR) of just 14 colonoscopies [23]

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[1] For gut health applications, the oral route has the most direct mechanistic support

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However, for someone whose toxic load has maxed out their detox systems, a particular toxin can begin to have detrimental effects that can manifest as neurological issues, autoimmune disorders, mental health changes, or systemic chronic illness

Colitis often involves periods of flare-ups and remission, where symptoms can come and go