So in recent years, GLP-1s have moved past diabetes from obesity to cardiovascular health
Crit Rev Biochem Mol Biol 48:119
Studies show the compounds natural mechanism reduces the risk of serious adverse events compared to direct growth hormone administration
In a 3-month randomized controlled study of type 2 diabetes, it was found that the combination of liraglutide and sitagliptin had no effect on the composition of intestinal flora, had no effect on the alpha and beta diversity, but liraglutide resulted in an elevation of deoxycholic acid (DCA) levels, indicating potential modulation of bile acid metabolism (Smits et al., 2021)
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