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Dysbiosis impairs the intestinal barrier, increasing its permeability and allowing bacteria and lipopolysaccharides (LPS) from the gut to translocate into the systemic circulation, leading to systemic inflammation (148)

( g-j ) Biodistribution analysis performed by 11C-SANA (9 MBq/animal) followed by PET-MRI scan

These drugs are sold in the USA under the brand names of Ozempic, Wegovy, and Rybelsus