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In vivo therapeutic effect of B2M-CuS NPs in OA mice To investigate the therapeutic effect of B2M-CuS NPs on OA, we established a DMM mouse model and delivered NPs into knee joints via intra-articular injection on a q14dx2 course (every 2 weeks for 4 weeks
These operational arguments might bring the long-standing theory into practice, starting with the initial argument of the lack of degradation in human gastric juice for periods of time longer than 24 h (for review see, [1,3,4,5,6,9,32,33,34,92]), and thereby its therapeutic effectiveness (including via a therapeutic per-oral regimen) and pleiotropic beneficial effect (for review see, i.e., [1,3,4,5,6,9,32,33,34,92])
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Trinkaus et al., 2020)
doi: 10.1080/10236244.2021.1923369 81 WitzgallP.KirschP.CorkA
