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After locking with a disulfide-forming reagent, BiLockCatcher has two independent reaction sites for SpyTag, one of which is constitutively active, and one which is inactive and can be unlocked on demand

Oral administration would break it down in the digestive tract

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Calcitonin gene-related peptide (CGRP) inhibits apoptosis in human osteoblasts by beta-catenin stabilization

PMID: 167 MesenTBYoungSL