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Molecular dynamics (MD) simulations, mass spectrometry and E194A site-directed mutagenesis revealed that PARP1-mediated ribosylation of PXR E194 enhanced CYP3A4 transcription, ultimately leading to excessive NAPQI production

10.1016/j.numecd.2025.103907 31 GuoC.ZhangT.DuL.YuK.ZengS.LiM.et al (2025a)

Appearance: White/off-white powder

K., Monaghan, E

Visible absorption in the 500 to 600 nm region is the standard bench check on copper complex integrity, and a colourless solution indicates the complex has been disrupted rather than simply diluted

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