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In the acute phase, symptoms include euphoria, anxiety, paranoia, and psychomotor agitation, which are primarily caused by the short-term overactivation of neurotransmitter systems ( 2.3.1 Cognitive impairment METH abuse significantly impairs cognitive function by targeting key brain regions ( 2.3.2 Psychiatric symptoms METH abuse disrupts the functionality of various brain regions, including the prefrontal cortex, nucleus accumbens, and thalamus, leading to significant psychiatric disturbances ( 2.3.3 Motor dysfunction Motor dysfunction caused by METH abuse is commonly characterized by parkinsonian-like symptoms, including tremors, bradykinesia, and rigidity (Yang et al., 2018)

Therefore, serum B 12 values above the cut-off point of deficiency do not necessarily confirm adequate B 12 status

Emerging nondopaminergic medications for parkinsons disease: focusing on A2A receptor antagonists and GLP1 receptor agonists

Understanding these multifaceted benefits helps explain why this peptide has generated significant interest in both research and clinical settings

Dietary intake of B vitamins and methionine and breast cancer risk

The human metabolic models with all constraints for the blood medium and the viral replication reactions have been uploaded to the BioModels Database 93 (Table 3) under the following accessions: Dengue, Influenza, SARS-CoV-2 BALF1, SARS-CoV-2 BALF2, SARS-CoV-2 CALU3, SARS-CoV-2 scH1299, Figure source data can be found in Supplementary Data 3