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Change history 10 April 2026 The original online version of this article was revised: Corresponding authors have been updated

While only certain GLP-1 medications are FDA-approved to treat obesity, others are being used off-label for their weight loss benefits

The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

Researchers must comply with all applicable institutional, state, and federal regulations governing the use of research chemicals

For MedTech developers, investors, and even consumers, understanding this divide is key not just for compliance but for market longevity, data credibility, and clinical relevance

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