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Semaglutide is a GLP-1 receptor agonist, while tirzepatide acts on both GIP and GLP-1 pathways, which is part of why both have become such important tools in modern obesity medicine (FDA Wegovy label

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The short answer is yes, it can happen, and it is more common than most people expect

Participants were randomly assigned to receive either the higher dose, the standard dose, or a placebo drug once a week for a period of 72 weeks

Have a high BMI (30 or more) indicating a need for medical weight management