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Back Hendershot, CS, Bremmer, MP, Paladino, B, et al (12 Feb 2025) 'Once-weekly semaglutide in adults with alcohol use disorder: A randomized clinical trial', JAMA Network, 82/4, 395-405.Back 'Scientists pioneer two techniques to combat obesity', The Guardian

It shows that members who used the Noom GLP-1 Companion app most frequently achieved greater weight lossand a higher rate of medication program persistencecompared with less-engaged peers

At 48 weeks in the Phase 2 trial, weight-loss curves were still declining participants had not reached a plateau

In the 2022 SURMOUNT-1 study published in NEJM, three doses of tirzepatide were compared with placebo (1:1:1:1) to determine effects on percent weight change over the course of 72 weeks

But cost is increasingly defining Americans experience with GLP-1s

The first medications the FDA approved in this class were injectables, though oral GLP-1s have since made their way to the market