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NVU coupling relies heavily on the canonical Wnt/-catenin, Sonic Hedgehog (SHH), PDGF-, and TGF- signaling pathways (123, 124)

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Meningococci may be able to invade epithelial cells in areas where the mucus layer is interrupted possibly due to inflammation or the activity of the resident microbiota that is able to attack the mucus, for instance by hydrolysis of glycans ( Streptococcus anginosus , S

10.1016/j.arcmed.2006.03.008 [DOI] [PubMed] [Google Scholar] 52.Al-Arfaj, A