Researchers handling any of these compounds are responsible for compliance with applicable law and institutional review requirements, including the Federal Food, Drug, and Cosmetic Act (21 U.S.C
P., Stamler, A., Vered, Y., Vidne, B
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6a, 6b)
Additionally, there are other systems independent of GPX4 that regulate ferroptosis, such as ferroptosis suppressor protein 1 (FSP1)/ubiquinone (CoQ10) [23], dihydroorotate dehydrogenase (DHODH) [24], GTP cyclohydrolase-1 (GCH1)/tetrahydrobiopterin (BH4) [25], and amino acid oxidase interleukin-4-induced-1/indole-3-pyruvate [26]