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Investigations of apoptosis dysregulation and chemoresponses in chronic lymphocytic leukemia

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A study using transfected CHO cells expressing recombinant rGLP-1R demonstrated that GLP-1(9-36)amide displayed a 94-fold reduced affinity compared with GLP-1 and produced approximately 50% of the cAMP levels at 1 M compared with that produced by 10 nM GLP-1 (Montrose-Rafizadeh et al ., 1997)

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Real-time Polymerase Chain Reaction (real-time PCR) The primary ESCs in each group and EEC/12Z were collected and used for RNA extraction