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From a clinical translation viewpoint, the most major challenge for aptamer medicines is their stability, particularly their sensitivity to fast nuclease breakdown and renal clearance

functional and/or structural moieties such as carbohydrates, fats, proteins or peptides, antibodies, receptors, hormones, cytotoxic substances, marker substances, dyes, radioactive labels, immunomodulatory agents, drugs, carriers, targeting or signalling substances, etc

A 1 mL syringe can be paired with different needle gauges, and the same gauge can appear with different syringe barrel sizes

Ann Pharmacother 42:16861691

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Compartmentation and reduction of pyridine nucleotides in relation to photosynthesis