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These qualitative observations provide encouragement during early phases when density changes remain minimal

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Diabetic ketoacidosis rarely is associated with triggering destruction of G6PD-deficient red cells

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Higher-risk patients include those in the dose-escalation phase, those with nausea, vomiting, bloating, abdominal pain, early satiety, or reflux symptoms, those on higher doses with GI side effects, and those with known gastroparesis or other conditions that slow gastric emptying