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Future research should focus on elucidating the key functional pathways implicated in clinical disease and on improved rehabilitation protocols

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To limit the narrative of the review, and to enhance its translational potential, we chose to exclude in vitro studies using immortalized cells or primary hepatocytes treated with NAC

25,26,27 We also previously showed that these cells exhibit low immunogenicity and exert immunosuppressive effects through PGE2-induced T-cell anergy, 28 and regulate humoral immune responses by secreting interleukin-6, which enhances B-cell viability while inhibiting B-cell proliferation, differentiation, and migration

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10.1093/gerona/glu057 91 FranklinR