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In cognitive peptides: substitute when possible in vivo tests by cerebral organoids or primary neuronal cultures ( Replacement ), optimise experimental plan to minimise the number of animals ( Reduction ), use appropriate anaesthesia and analgesia during invasive procedures ( Refinement )

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Our BPC-157 is manufactured in China in GMP-compliant facilities with high-purity (99%) pharmaceutical-grade quality , supplied as a stable lyophilized powder for flexible formulation work in the lab

A gut-brain neural circuit for nutrient sensory transduction

therefore, comparisons with other studies using absolute weight and BMI measures should be interpreted with caution