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Another study found that the gut microbiota of patients with CHE were characterized by loss of Eubacteriaceae and Sutterellaceae , including Eubacterium , Lachnospira , Parasutterella , and Erysipelotrichaceae , and enrichment of Clostridiales , including Odoribacter , Flavonifractor , and Coprobacillus [71]

& Hemmati, S

When it was noticed that they had a side effect of a small amount of weight loss, the manufacturers got the idea to give people higher doses to see if that would cause more of whatever side effects created the weight loss

Clinical trials show weight losses of ~6%16%