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Oral insulin provides a solution to these challenges, as it is considered to mimic the endogenous release of insulin 17

In humans, exercise induces endogenous MOTS-c expression in skeletal muscle and in circulation

doi:10.1023/A:1024931311845 PMID:12910291 Korkushko OV, Khavinson VKh, Shatilo VB, Antonyk-Sheglova IA

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The peptide has been used to treat poor sleep, pain conditions, stress-related symptoms, and more

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