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10.1016/j.ajp.2021.102896 79 RabbaniG

The 28-day rule exists to minimize that risk as much as possible

Imposing Step Therapy/Fail-First Programs for Weight Loss

LegitScript Findings: Explosive Ad Growth: LegitScript tracks online activity across major platforms, and our monitoring of online ads has revealed a more than 200% increase in violative or problematic GLP-1-related ads in the first half of 2024 compared to all of 2023, and a roughly 1200% increase compared to all of 2022

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, et al

Repeated cycling amplifies these risks and should only be done with close clinical monitoring