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[8] This suggests that for some, the calming effect of the drug applies to their mood as much as their appetite

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In the United States, prescribing information for all medications licensed for obesity that act on the CNS, including the GLP-1RAs liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy), must include the recommendation of monitoring for depression and suicidal ideation 231

People using GLP-1a weight loss and diabetes medications, such as Ozempic and Mounjaro, experience a dramatic slowdown in their intestinal transit time down to just a fifth of the usual rate