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Once-Weekly Cagrilintide for Weight Management in Adults With Overweight and Obesity: A Phase 2 Trial

The percent (%) cytotoxicity was determined using the following formula for each given experimental treatment: Cytotoxicity (%) = 100 [(Experimental Culture Medium Background)/(Maximum LDH Release Culture Medium Background)]

Not necessarily higher doses, but older users often respond particularly well because their baseline GHK levels are lower

Data were normalised to GAPDH, and fold changes relative to the control group were calculated using the 2 CT method

The participants provided their written informed consent to participate in this study

10.1371/journal.pone.0013031 PLoS One