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Macrophage Function in Obesity-Induced Inflammation and Insulin Resistance

Although the exact reason behind ageing is yet to be clear, several evidences suggest on damage-based theories

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Islets were obtained from normoglycemic donors, according to the local ethics rules (including next-of-kin consent) and isolation techniques, and cultured in RPMI supplemented with 5.5 mM d-glucose, 10% FCS, 100 U penicillin, 100 g streptomycin, and 0.25 g l 1 fungizone (37 C, 5% CO 2 ) 28

Animals and Tissue Collecting SpragueDawley rats were used to determine if bacterial products could activate enteric neurons and the vagus nerve across an intact, non-leaky colon (Gareau et al., 2007)

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