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Dihexa is reported to be active at picomolar concentrations in synaptogenesis assaysapproximately 10,00010,000,000-fold more potent than BDNF (brain-derived neurotrophic factor) in some in vitro measures, though this comparison involves different assay conditions and should not be taken as a direct clinical equivalence claim

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Injectable administration delivers systemic cellular access rather than the localized effects of topical copper peptide products

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The authors noted NNMT overexpression in many human malignancies and described 5-Amino-1MQ as a novel NNMT inhibitor with promising results across obesity and cancer cell research models