In September 2023 the FDA placed roughly 19 peptide substances into Category 2 of its interim 503A bulks list, meaning the agency had identified potential significant safety risks and compounding pharmacies could not use them
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All statistical analyses and graphs were performed using GraphPad Prism software version 7 (GraphPad Software, Inc., La Jolla, CA, USA)
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Use should be discontinued upon observing any adverse reaction
[23] Additionally, a 2018 observational study suggested an elevated risk of developing inflammatory bowel disease, specifically ulcerative colitis, which peaked after three to four years of use and decreased after more than four years