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Although it remains a viable option both for managing blood sugar levels and assisting with some degree of weight reduction, its inferior benefits combined with a more demanding dosing regimen makes it less desirable among available treatments

Data from Phase 2 trials (NEJM, 2023) indicate that these effects are generally mild to moderate and transient

In the future, more GLP-1RAs will be explored for the improvement of ischemic stroke and cognitive impairment in patients with diabetes [190]

The most frequent adverse events associated with resmetirom were diarrhea and nausea

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Cagrilintide is also dosed in mg but at much lower doses (0.25-2.4 mg range)