The researchers proposed that the compounds effects on muscle function operate through boosting NAD+ levels by inhibiting NNMTs consumption of nicotinamide, more substrate is available for NAD+ synthesis via the salvage pathway, supporting mitochondrial function and energy metabolism in aged skeletal muscle
(2023) JAMA Netw Open, 6: e2340859
they offer one data point within a comprehensive health evaluation
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This natural decrease is a major reason why skin texture changes, color shifts, and wrinkles begin to form as we age