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In addition, to prevent fluvastatin repressing vascular reactions to histamine, mice were pre-treated with fluvastatin and by infusing histamine the activity of mast cells was inhibited, which created conditions in which fluvastatin had no effect

A recent study demonstrated that the ability of a p53 variant, a nonsynonymous single-nucleotide polymorphism referred to as P47S found in people of African descent, to transactivate GLS2 was impaired [120, 126]

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