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These results were confirmed by RT-PCR analysis (Fig

Researching the difference between the two kinds of arbutin, you can read in multiple places on the internet that alpha-arbutin is stronger in effect

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A reduction of the N-terminal peptide bond of 25 , with the ambition to achieve a compound even more resistant to proteolytic cleavage, provided 26 (Barlow et al., 2020)

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doi: 10.1016/j.molmet.2023.101738