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This is not because the evidence is weak

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Wood pointed to one large observational study from the U.S

CPT1 is a key enzyme in lipid metabolism as it catalyzes the rate-limiting step in beta oxidation 12, 36

A 2024 study from the International Foundation of Employee Benefit Plans showed that employer coverage of GLP-1s is still limited, with 34% of corporate plans currently providing coverage for non-diabetic patients who want to lose weight (up 8 percentage points from 2023)

Heres the science explained simply in everyday terms: Your cells have an enzyme called NNMT that becomes overactive when youre carrying extra weight (especially in fat tissue)