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FOXO4 plays a key role in regulating cell cycle control, stress resistance, and apoptosis, while p53 is a central regulator of DNA damage response and cellular aging

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Environmental and molecular mutagenesis , 58 (2), 6071

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Yes, but clinical trial data shows cagrilintide monotherapy produces 68% body weight reduction at 20 weeks, compared to 15.1% when combined with semaglutide in the CagriSema trial